OUR TEAM 



XingXing Zang, M.Med, Ph.D.

 

Louis Goldstein Swan Chair in Cancer Research

Professor,  Department of Microbiology & Immunology

Professor,  Department of Oncology

Professor,  Department of Medicine

Professor,  Department of Urology

Albert Einstein College of Medicine


Office:      Forchheimer Building 405

Phone:      718-430-4155

Email:        xingxing.zang@einsteinmed.edu

Twitter:    @xingxing_zang

LinkedIn:  https://www.linkedin.com/in/xingxing-zang-7722757


M.Med: Shanghai Jiao Tong University School of Medicine

Mentor: BaoLi Ma

PhD: University of Edinburgh

  Mentor: Rick M. Maizels

Fellow: University of California at Berkeley

  Memorial Sloan-Kettering Cancer Center

Mentor: James P. Allison (2018 Nobel laureate in Physiology or Medicine)

Current Lab Members

Devin T. Corrigan,  M.S.

PhD Student

Department of Microbiology & Immunology

Albert Einstein College of Medicine

Forchheimer Building, Room 411

Bronx, NY 10461

Tel: 718-430- 3245

Email: devin.corrigan@einsteinmed.edu

Devin Corrigan received his B.S. in Biological Sciences and Spanish from Binghamton University in 2019. While at Binghamton University, he studied the mechanisms of persistence and potential treatments for P. aeruginosa biofilms under Drs Light and Boyko. After graduation, he joined the lab of Dr. Achkar at Albert Einstein College of Medicine to study the host immune response to M. tuberculosis infection. Here he studied the human and non-human primate antibody responses to Mtb to improve diagnostic testing and further our understanding of antibodies as correlates of protection to activation of Mtb and progression to disease. He started in the PhD program at Albert Einstein College of Medicine in the fall of 2021, and joined the Zang lab in July 2022. In the Zang lab he is working on understanding and targeting new immune checkpoint pathways.

 

Publications:

Pulanco MC, Madsen AT, Tanwar A, Corrigoan DT, Zang X. Recent advancements in the B7/CD28 immune checkpoint families: New biology and clinical therapeutic strategies.   Cellular & Molecular Immunology, 20:694-713, 2023

Ren X*, Corrigan D*, Zang X.  Protocol for evaluating anti-tumor activity of KIR3DL3 blockade in an NK cell-based xenogeneic lung tumor model. STAR Protocols, 3:101818. doi: 10.1016/j.xpro, 2022   (*Co-first author)

Ren X, Peng M, Xing P, Wei Y, Galbo PM, Corrigan D, Wang H, Su Y, Dong X, Sun Q, Li Y, Zhang X, Edelmann W, Zheng D, Zang X.  Blockade of the immunosuppressive KIR2DL5-PVR pathway elicits potent human NK cell-mediated anti-tumor immunity.   Journal of Clinical Investigation, 132:e163620. doi: 10.1172/JCI163620, 2022

Corrigan DT, Ishida E, Chatterjee D, Lowary TL, Achkar JM. Monoclonal antibodies to lipoarabinomannan/arabinomannan – Characteristics and implications for Tuberculosis research. Trends in Microbiology, 31:22-35, 2023

Ishida E, Corrigan DT, Malonis RJ, Hofmann D, Chen T, Amin AG, Joe M, Lowary TL, Lai JR, Achkar JM. Monoclonal antibodies from humans with Mycobacterium tuberculosis exposure or latent infection recognize distinct arabinomannan epitopes. Communications Biology, 4:1181. doi: 10.1038/s42003-021-02714-w, 2021.

Zidong (Andy) Li ,  Ph.D.

 

Research Fellow

Department of Microbiology & Immunology

Albert Einstein College of Medicine

Forchheimer Building, Room 405

Bronx, NY 10461

Tel: 718-430-4154

Email: zidong.li@einsteinmed.edu  

Zidong (Andy) Li received his BSc in Biological Resource Science at the University of Tsukuba, Japan, and his MSc in Molecular Biology at the University of Queensland, Australia. He then joined the lab of Dr. Park at Massey University, New Zealand, to study a novel epigenetic protein complex in cancer immune evasion, and earned his PhD in 2023. His PhD project aimed to understand the transcriptional regulatory mechanisms regulating the expression of PD-L1 in cancer cells by exploring unknown chromatin-remodelling complexes (EP400NL associated). In January 2024, he joined Prof. Zang's lab as a postdoctoral fellow, where he is currently working on new immune checkpoints and exploring strategies for improving cancer immunotherapy.

 

Publications:

Li Z, Kim H, Kim J, Park JH. EP400NL is involved in PD-L1 gene activation by forming a transcriptional coactivator complex. Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms, 1866:194889, 2023

Bai S, Yao Z, Zhu X, Li Z, Jiang Y, Wang R, Wen N. The feasibility and safety of reproductive organ preserving radical cystectomy for elderly female patients with muscle-invasive bladder cancer: a retrospective propensity score-matched study. Urology, 125:138-145, 2019

Bai S, Yao Z, Zhu X, Li Z, Jiang Y, Wang R, Wen N. Risk factors for postoperative cardiovascular morbidity after pheochromocytoma surgery: a large single center retrospective analysis. Endocrine Journal, 66: 165-173, 2019

Bai S, Yao Z, Zhu X, Li Z, Jiang Y, Wang R, Wu B. Comparison of transperitoneal laparoscopic versus open adrenalectomy for large pheochromocytoma: a retrospective propensity score-matched cohort study. International Journal of Surgery, 61:26-32, 2019

Bai S, Yao Z, Zhu X, Li Z, Jiang Y, Wang R, Wu B. Risk factors for postoperative severe morbidity after pheochromocytoma surgery: a single center retrospective analysis of 262 patients. International Journal of Surgery, 60:188-193, 2018

Amit K Mishra,  Ph.D.

 

Research Fellow

Department of Microbiology & Immunology

Albert Einstein College of Medicine

Forchheimer Building, Room 411

Bronx, NY 10461

Tel: 718-430-3245

Email: amit.mishra@einsteinmed.edu 

Amit Mishra graduated in Biochemistry (H) from the University of Delhi, India. He was rewarded with fellowship and earned his PhD degree from South Asian University, New Delhi, India. During his PhD tenure, he identified three host proteins that act as restriction factors against Hepatitis B virus, and elucidated the mechanism involved in novel host restriction factor mediated inhibition of HBV replication as well as the counteraction mechanism employed by the virus to overcome the inhibitory host restriction proteins. He was also part of project including metabolic disorder non-alcoholic fatty liver disease, liver fibrosis, and hepatocellular carcinoma. In April 2023, he joined Prof. Zang’s lab and is currently working on novel immune checkpoints and metabolic pathways.

 

Publications:

Mishra AK, Hossain M, Umar Md, Sata TN, Yadav AK, Zadran S, Sah AK, Ismail Md, Nayak B, Shalimar, Venugopal SK. DDX3-mediated miR-34 expression inhibits autophagy and HBV replication in hepatic cells. Journal of Viral Hepatitis, 30:327-334, 2023


Mishra AK, Hossain M, Sata TN, Yadav AK, Zadran S, Sah AK, Nayak B, Shalimar, Venugopal SK. Hepatitis B virus X protein inhibits the expression of Barrier to autointegration factor1 via upregulating miR-203 expression in hepatic cells. Microbiology Spectrum, 11: e0123522, 2022


Yadav AK, Sata TN, Verma D, Mishra AK, Sah AK, Hossain MM, Pant K, Venugopal SK. Free fatty acid-induced miR-181a-5p stimulates apoptosis by targeting XIAP and Bcl2 in hepatic cells. Life Sciences, 301:120625,  2022


Sharma D, Jain S, Mishra AK, Sharma R, and Tanwar A. Medicinal herbs from Phytoinformatics: An aid for skin burn management,” Current Pharmaceutical Biotechnology, 23:1436-1448, 2022


Gupta P, Sata TN, Ahamad N, Islam R, Yadav AK, Mishra AK, Nithyananthan S, Thirunavukkarasu C, Sanal MG, Venugopal SK. Augmenter of liver regeneration enhances cell proliferation through the microRNA‐26a/Akt/cyclin D1 pathway in hepatic cells. Hepatology Research, 49:1341-52, 2019 

Gupta P, Sata TN, Yadav AK, Mishra AK, Vats N, Hossain MM, Sanal MG, Venugopal SK. TGF-β induces liver fibrosis via miRNA-181a-mediated down regulation of augmenter of liver regeneration in hepatic stellate cells. PLoS ONE, 14:e0214534, 2019 

Pant K, Mishra AK, Pradhan SM, Nayak B, Das P, Shalimar, Saraya A, Venugopal SK. Butyrate inhibits HBV replication and HBV-induced hepatoma cell proliferation via modulating SIRT-1/Ac-p53 regulatory axis. Molecular Carcinogenesis, 58:524–532, 2019

Marc C. Pulanco, M.S.

 

PhD Student

Department of Microbiology & Immunology

Albert Einstein College of Medicine

Forchheimer Building, Room 405

Bronx, NY 10461

Tel: 718-430-4154

Email: marcchristopher.pulanco@einsteinmed.edu

Marc Pulanco earned his M.S. and B.S. in Biology from California State University Long Beach in 2018 and 2015 respectively. There, he worked in Dr. Deborah A. Fraser’s lab studying the role of complement protein, C1q, of the innate immune system in atherosclerosis. As an undergraduate, he studied the effect of C1q on macrophage foam cell survival and the anti-apoptotic mechanisms involved. For his master, he examined the effect of C1q on lipid metabolism of macrophage foam cells to promote their survival. Marc joined the PhD program at Albert Einstein College of Medicine in 2018 with the intention of studying immunology in any disease to develop novel immunotherapies. He joined the Zang lab in July 2019 and is investigating the therapeutic potential of new immune checkpoint members in urothelial cancer, graft-versus-host disease, and type 1 diabetes.

 

Publications:

Liu Y, John P, Christin JR, Nishimura CD, Couturier N, Ren X, Galbo P, Wei Y, Pulanco MC, Cui J, Cui W, Bartholdy BA, Zheng D, Lauvau G, Oktay MH,  Zang X, Guo W. A SOX9-B7x axis safeguards dedifferentiated cells from immune surveillance to drive breast cancer progression.    Developmental Cell, 58:2700-2717, 2023


Pulanco MC, Madsen AT, Tanwar A, Corrigoan DT, Zang X. Recent advancements in the B7/CD28 immune checkpoint families: New biology and clinical therapeutic strategies.   Cellular & Molecular Immunology, 20:694-713, 2023


John P, Pulanco MC, Galbo PM, Wei Y, Ohaegbulam KC, Zheng D, Zang X. The immunecheckpoint B7x expands tumor-infiltrating Tregs and promotes resistance to anti-CTLA-4 therapy.   Nature Communications, 13:2506. doi: 10.1038/s41467-022-30143-8, 2022

Nishimura CD*, Pulanco MC*, Cui W, Lu L, Zang X. PD-L1 and B7-1 cis-interaction: New mechanisms in immune checkpoints and immunotherapies.  Trends in Molecular Medicine, 27:207-219, 2021 (*Co-first author)

Bortz RH, III, Wong AC, Grodus MG, Recht HS, Pulanco MC, Lasso G, Anthony SJ, Mittler E, Jangra RK, Chandran K. A virion-based assay for glycoprotein thermostability reveals keydeterminants of filovirus entry and its inhibition. Journal of Virology, 94:e00336-20, 2020

Pulanco MC, Cosman J, Ho MM, Huynh J, Fing K, Turcu J, Fraser DA. Complement Protein C1q Enhances Macrophage Foam Cell Survival and Efferocytosis. Journal of Immunology, 198: 472-480, 2017

Yunchao Shentu, B.S.

 

PhD Student

Department of Microbiology & Immunology

Albert Einstein College of Medicine

Forchheimer Building, Room 411

Bronx, NY 10461

Tel: 718-430-3245

Email: yunchao.shentu@einsteinmed.edu

Yunchao Shentu obtained his B.S. in Pharmacy from Sichuan University, China in 2022. While at Sichuan University, he studied regulation mechanism of cardiac hypertrophy under the supervision of Professor Bisen Ding. After graduation, he furthered his research experience by joining the lab of Dr. Dehua Chang at the University of Tokyo, Japan, where he studied the three-dimensional culture of umbilical cord-derived mesenchymal stem cells. In the autumn of 2023, Yunchao commenced PhD program at Albert Einstein College of Medicine and joined the Zang Laboratory in the same year. In the Zang lab he is working on basic biology and translational immunotherapy of new immune pathways.


Publications:

Zhu S, Xuan J, Shentu Y, Kida K, Kobayashi M, Wang W, Ono M, Chang D. Effect of chitin-architected spatiotemporal three-dimensional culture microenvironments on human umbilical cord-derived mesenchymal stem cells.   Bioactive Materials, 35:291-305, 2024.

Roberto Alejandro (Alex) Sica, M.D.

 

Assistant Professor, Department of Oncology

Assistant Professor, Department of Medicine

Montefiore Medical Center

Hofheimer Main, Room 100

Tel: 718-920-4826

Fax: 718-798-7474

Albert Einstein College of Medicine

Forchheimer Building, Room 405

Bronx, NY 10461

Email: asica@montefiore.org

Alex completed medical school at the University of Buenos Aires, in Argentina where he also worked as an instructor in immunology, virology, pharmacology and physical diagnosis. He also did basic lab research work studying the cytotoxic effects of NK-cells in endometriosis.  He then moved to the United States and worked at Dr. Warren Pear’s laboratory at the University of Pennsylvania on Notch1 and NF-kappa B in T-cell development. He continued his research at the University of Pittsburgh, where he studied the role of ATM in the phosphorylation of Ku70 in DNA damage response. Later, at the University of California at Davis, he studied the biochemical mechanisms of DNA homologous recombination and showed that RAD52 mediates second 3’-end capture and double Holliday junction formation with Dr. Stephen Kowalczykowski.  He then started his residency in internal medicine at the Caritas Carney Hospital, Tufts University and while in Boston, he performed clinical research in double cord blood transplants at the Massachusetts General Hospital with Dr. Karen Ballen.  Later he joined the University of Illinois at Chicago for his fellowship in Hematology and Medical Oncology.  He helped design clinical trials using Pembrolizumab and Bevacizumab for renal cell carcinoma with Dr. Arkadiusz Dudek.  He later moved to Stanford University, Palo Alto, CA for an advanced clinical fellowship in Stem Cell Transplant and Cancer Immunotherapies.  He was exposed to multiple CAR-T cell therapies including CART CD19, CART BCMA and the Stanford led CD19/CD22 bispecific CAR-T cells for DLBCL. He then joined Montefiore Center for Cancer Care/Albert Einstein College of Medicine as an Assistant Professor in hematologic malignancies, bone marrow transplant and CAR-T cell therapies.  In the Zang lab, he is studying the role of novel checkpoints in hematologic malignancies as well as their potential connection with distinct mutational profiles and chemotherapy responses to explore new therapeutic opportunities.  His main area of interest is to help with the CAR-T cell lab efforts in hematologic malignancies and to assist in their translational applications in clinical trials.

 

Publications

Wang H, Sica RA, Kaur G, Galbo PM Jr, Jing Z, Nishimura CD, Ren X, Tanwar A, Etemad-Gilbertson B, Will B, Zheng D, Fooksman D, Zang X.  TMIGD2 is an orchestrator and therapeutic target on human acute myeloid leukemia stem cells.    Nature Communications, 15:11. doi: 10.1038/s41467-023-43843-6, 2024

Wei Y, Ren X, Galbo PM, Moerdler S, Wang H, Sica RA, Etemad-Gilbertson B, Shi L, Zhu L, TangX, Lin Q, Peng M, Guan F, Zheng D, Chinai JM, Zang X. KIR3DL3-HHLA2 is a human immunosuppressive pathway and a therapeutic target.   Science Immunology, 6:eabf9792, 2021

Acuna-Villaorduna A, Gonzalez-Lugo J, Ye BH, Adrianzen Herrera DA, Sica RA, Shah U, Shah N, Kornblum N, Braunschweig I, Derman O, Mantzaris I, Shastri A, Wang Y, Verma A, Zalta B, Janakiram M.  High prevalence of pulmonary findings in computed tomographies of HTLV-1-infected patients with and without adult-T cell leukemia/lymphoma - implications for staging. Leukemia & Lymphoma. 17:1-5, 2019

Adrianzen Herrera D, Kornblum N, Acuna-Villaorduna A, Sica RA, Shah U, Butler M, Vishnuvardhan N, Shah N, Bachier-Rodriguez L, Derman O, Shastri A, Mantzaris I, Verma AK, Braunschweig I, Janakiram M. Biology of Blood and Marrow Transplantation. 25(6):e199-e203, 2019

Adrianzen Herrera D, Kornblum N, Derman O, Bachier-Rodriguez L, Sica RA, Shastri A, Janakiram M, Verma A, Braunschweig I, Mantzaris I.  Outcomes of autologous hematopoietic cell transplantation compared with chemotherapy consolidation alone for non-high-risk acute myeloid leukemia in first complete remission in a minority-rich Inner-city cohort with limited access to allografts. Clinical Lymphoma Myeloma and Leukemia. 19:516-521, 2019

Nikiforow S, Li S, Snow K, Liney D, Kao GS, Haspel R, Shpall EJ, Glotzbecker B, Sica RA, Armand P, Koreth J, Ho VT, Alyea EP 3rd, Ritz J, Soiffer RJ, Antin JH, Dey B, McAfee S, Chen YB, Spitzer T, Avigan D, Cutler CS, Ballen K. Lack of impact of umbilical cord blood unit processing techniques on clinical outcomes in adult double cord blood transplant recipients. Cytotherapy. 19:272-284, 2017

Sica RA., Jefferson G., Wenig BL, Aakalu V, Chen L, Kolokythas A, Spiotto MT, Patel D, Cuellar S, Domingo G, Feldman LE. Vismodegib as neoadjuvant for orbital recurrent basal cell carcinoma facilitates eye-sparing tumor excision. Anticancer Research Journal. 35: 6695-6704, 2015

Nimonkar AV, Sica RA,  Kowalczykowski SC.  Rad52 promotes second-end DNA capture in double-stranded break repair to form complement-stabilized joint molecules. Proceedings of the National Academy of Sciences USA. 106:3077-82, 2009.

Xiaona Sun, Ph.D.

 

Research Fellow

Department of Microbiology & Immunology

Albert Einstein College of Medicine

Forchheimer Building, Room 411

Bronx, NY 10461

Tel: 718-430-3245

Email:  xiaona.sun@einsteinmed.edu   

Xiaona Sun received her PhD from Wuhan University in 2023. During her PhD, she focused on antiviral innate immunity. She found that the kinase DNA-PK (DNA-dependent protein kinase, DNA-PK) inhibited the cytoplasmic DNA receptor cGAS (cyclic GMP-AMP synthase) enzymatic activity by phosphorylating cGAS, thereby regulating the antiviral innate immune response. In addition, she was also involved in tumor immunity-related research demonstrating that STING (stimulator of interferon genes) inhibited glycolysis by targeting HK2 (Hexokinase II, HK2), thereby reducing the production of lactic acid, inhibiting the acidification of the tumor microenvironment, and promoting tumor immunity. In 2024, she joined Prof. Zang's lab as a postdoctoral fellow, where she is studying the mechanisms of new immune checkpoint pathways and developing new immunotherapies.


Publications:

Zhang L, Jiang C, Zhong Y, Sun K, Jing H, Song J, Xie J, Zhou Y, Tian M, Zhang C, Sun X, Wang S, Cheng X, Zhang Y, Wei W, Li X, Fu B, Feng P, Wu B, Shu HB, Zhang J. STING is a cell-intrinsic metabolic checkpoint restricting aerobic glycolysis by targeting HK2.     Nature Cell Biology, 25:1208-1222, 2023                                    


Sun X, Liu T, Zhao J, Xia H, Xie J, Guo Y, Zhong L, Li M, Yang Q, Peng C, Rouvet I, Belot A, Shu HB, Feng P, Zhang J.  DNA-PK deficiency potentiates cGAS-mediated antiviral innate immunity.  Nature Communications, 11:6182 doi: 10.1038/s41467-020-19941-0, 2020



Ankit Tanwar, Ph.D.

 

Staff Scientist

Department of Oncology

Department of Microbiology & Immunology

Albert Einstein College of Medicine

Forchheimer Building, Room 405

Bronx, NY 10461

Tel: 718-430-4154

Email: ankit.tanwar@einsteinmed.edu

Ankit Tanwar previously worked as a Post-Doctoral Scientist (2018-2022) with Prof. Stanley at Albert Einstein College of Medicine. He was working on Role of Notch Glycosylation in Hematopoiesis. Dr. Tanwar received his Ph.D. degree in Toxicology from the Institute of Nuclear Medicine and Allied Sciences, New Delhi, India in 2018 followed by his master degree in Toxicology in 2014 and bachelor degree in Biochemistry from Shivaji College, University of Delhi, New Delhi, in 2012. He was a key worker of a team who coined the word "Herbal Informatics", which has been used for the initial screening of emergency-approved drug by DCGI: 2-Deoxy-D-glucose (2-DG) for combating the COVID-19 situation in India. He is also serving as an Editorial Board and Co-chair of committees (JoLS/SoLS, USA and JoVE, USA, etc). In July 2022, he joined Prof. Zang's Lab and he is co-mentored by Dr. Alex Sica (Department of Oncology) and Prof. Zang (Department of Microbiology & Immunology). He is currently working on the function and mechanism of CAR-T cell therapy  and new immune checkpoints.


Publications:

Wang H, Sica RA, Kaur G, Galbo PM Jr, Jing Z, Nishimura CD, Ren X, Tanwar A, Etemad-Gilbertson B, Will B, Zheng D, Fooksman D, Zang X.  TMIGD2 is an orchestrator and therapeutic target on human acute myeloid leukemia stem cells.   Nature Communications, 15:11. doi: 10.1038/s41467-023-43843-6, 2024

Pulanco MC, Madsen AT, Tanwar A, Corrigoan DT, Zang X. Recent advancements in the B7/CD28 immune checkpoint families: New biology and clinical therapeutic strategies.   Cellular & Molecular Immunology, 20:694-713, 2023


Jaewon Yun, B.S. 

 

MD student

Albert Einstein College of Medicine

Forchheimer Building, Room 411

Bronx, NY 10461

Tel: 718-430-3245

Email: jaewon.yun@einsteinmed.edu 

Jaewon Yun received his B.S. in Molecular Biology from the University of California, Los Angeles in 2021. After graduation, he joined the biotechnology company Lyell Immunopharma in San Francisco. There he worked on Lyell Immunopharma’s proprietary tumor-infiltrating lymphocyte protocol, LYL845, to combat solid tumor cancers. Furthermore, his work on LYL845 helped to optimize the expansion process, allowing for improvement in T-cell stemness and overall reduction in the length of TIL expansion. He is currently a student in the MD program at Albert Einstein College of Medicine and joined the Zang lab in December of 2023. In the Zang lab he is working on understanding and targeting new immune checkpoint pathways.


Publications:

Wang S, Wang M, Ichino L, Boone BA, Zhong Z, Papareddy RK, Lin EK, Yun J, Feng S, Jacobsen SE. MBD2 couples DNA methylation to Transposable Element silencing during male gametogenesis.   Nature Plants, accepted.

 

Boone BA, Ichino L, Wang S, Gardiner J, Yun J, Jami-Alahmadi Y, Sha J, Mendoza CP, Steelman BJ, van Aardenne A, Kira-Lucas S, Trentchev I, Wohlschlegel JA, Jacobsen SE. ACD15, ACD21 and SLN regulate accumulation and mobility of MBD6 to silence genes and transposable elements.  Science Advances, 9: eadi9036, 2023

 

Ichino L, Picard CL, Yun J, Chotai M, Wang S, Lin EK, Papareddy RK, Xue Y, Jacobsen SE. Single-nucleus RNA-seq reveals that MBD5, MBD6, and SILENZIO maintain silencing in the vegetative cell of developing pollen.   Cell Reports, 41: 111699, 2022

Jiabi Zhang, M.S.

 

PhD Student

Department of Microbiology & Immunology

Albert Einstein College of Medicine

Forchheimer Building, Room 405

Bronx, NY 10461

Tel: 718-430-4154

Email: jiabi.zhang@einsteinmed.edu 

Jiabi Zhang received her M.S. in Biochemistry and Molecular Biology from Sichuan University in 2018. While at Sichuan University, she mainly focused on exploring the mechanism and intervention of the Th17/ Treg (regulatory T cell) imbalance in the development of organ inflammation in autoimmune diseases, including rheumatoid arthritis. Then, she obtained her M.S. in Biomedical Sciences from the University of Utah in 2023. There, she studied diabetes and obesity, investigated bone morphogenetic protein endothelial regulator which is a marker of adipose progenitors and adipocytes and a positive modulator of adipogenesis. In August 2023 she started in the PhD program at Albert Einstein College of Medicine and joined the Zang lab. In the Zang lab she is working on the function and mechanisms of novel immune checkpoints.


Publications:

Zhai X, Pu D, Wang R, Zhang J, Lin Y, Wang Y, Zhai N, Peng X, Zhou Q, Li L. Gas6/AXL pathway: immunological landscape and therapeutic potential.  Frontiers in Oncology,  13:1121130, 2023


Zhai X, Wang T, Lin Y, Zhang J, Wang Y, Wang W, Zhou Q, Zhu D. Case report: Complete pathological admission in N3 unresectable locally advanced lung adenocarcinoma with a novel INTS10-ALK and EML4-ALK fusion after neoadjuvant crizotinib.  Frontiers in Oncology, 13:1104910, 2023

 

Hamilton EM, Rassam W, Yan Y, Singh A, Ng SY, Zhang J,  Lv J, Islam N, Malouf R, Yang L, Millwood IY, Chen Z. Correlates of chronic hepatitis B virus infection in the general adult population of China: systematic review and meta‐analysis.  Journal of Viral Hepatitis, 30:470-488, 2023

 

Garritson JD, Zhang J, Achenbach A, Ferhat M, Eich E, Stubben CJ, Martinez PL, Ibele AR, Hilgendorf KI, Boudina S. BMPER is a marker of adipose progenitors and adipocytes and a positive modulator of adipogenesis.  Communications Biology, 6:638, 2023

 

Shan J, Zhang J. Impact of obesity on the efficacy of different biologic agents in inflammatory diseases: A systematic review and meta-analysis.  Joint Bone Spine, 86:173-183, 2019

 

Zhang J, Jin H, Xu Y,  Shan J. Rapamycin modulate Treg/Th17 balance via regulating metabolic pathways: A study in mice.  Transplantation Proceedings,  51:2136-2140, 2019

 

Li HS, Zhou YN, Li L, Li SF, Long, D, Chen XL, Zhang JB, Feng L, Li YP. HIF-1α protects against oxidative stress by directly targeting mitochondria.  Redox Biology, 25:101109, 2019

 

Zhang J, Shan J, Chen X, Li S, Long D, Li Y. Celastrol mediates Th17 and Treg cell generation via metabolic signaling.  Biochemical and Biophysical Research Communications, 497:883-889, 2018

 


Lab Alumni 



Chayim Z. Goldberg                        Nai Robert Li                                Sang C. Lee                            Nousheen Zaidi  

Lucas Cusumano                            Samarpit Rai                                  Jun Sik Lee                       Kimberly A. Hofmeyer 

Adina Sperling                            Yael M. Abadi                  Ruihua Zhao                   Kaya Ghosh

Anjana Ray                             Lisa Scandiuzzi                     Qi Lin                               Hyungjun Jeon

Amer Assal                             William Mitchell                     Xiaoshen Dong          Qizhe Sun       

Yvaguencia Michel                            Xudong Tang                               Yao Liu                       Ayobami Akenroye

Kim C. Ohaegbulam                 Jordan M. Chinai                 Linna Suo                            Murali Janakiram 

Shan Wang                             Scott Moerdler                   Xiaoyu Zhang         Yingzhen Su                    

ShengNan Yuan                            Shuyu Huang                             Peng Xing                    Damini Chand

Gurbakhash Kaur                            Lei Shi                                         Peter John                   Liqiang Zhu                   

Mou Peng                          Elodie Picarda                           Mali Barbi                   Yao Wei                   

Ethan Li                              Xiaoxin Ren                                    Phillip M. Galbo Jr                      Nicholas Samel                                                    

Hao Wang Anne T Madsen Christopher Nishimura